Endocannabinoid Course

with David Krantz

With the massive growth in the cannabis and CBD markets, your clients are interested in or already using cannabinoids whether you're prepared to help them or not. The CannaDNA course is a deep dive into how genetics influence the individual response to cannabis and will certify you to use the Apeiron Endocannabinoid Panel in your practice.

That way you can help your clients make informed decisions while giving you an additional income-producing offering that will set your services apart.

In this course, you'll learn how to:

  • Identify if clients are good candidates for cannabisDetermine optimal dosage ranges

  • Text length of individual points can be shorter or longer depending on your needs

  • ​Reduce risk for drug/drug interactions

  • ​Prevent unwanted cognitive side effects

  • Guide personalized strain and product selection

  • Improve client outcomes and optimize use of cannabinoids

  • ​Interpret the Apeiron Genomics Endocannabinoid Panel and understand other Tests on the Market

  • Use genetic interpretation best practices for more effective results

  • Based on 183 peer-reviewed references, each module covers the scientific literature in-depth and shows you how to apply it directly to your clients using the Apeiron Endocannabinoid Panel.



    Overview of the Endocannabinoid System - Get clear on the science and function of cannabinoid receptors, endogenous cannabinoids, enzymes, and more so you have solid foundation to work from.


    Modulating the Endocannabinoid System - Learn all the ways to shift endocannabinoid function through exogenous cannabinoids, terpenes, and dietary and lifestyle factors so you can create precise custom protocols.


    Cognitive Function and THC - Identify which genetic variants are protective factors against things like short term memory dysfunction with THC, impaired reaction time or impulsivity, brain structure changes, so you can help clients reduce risk and choose the right products.


    CBD Metabolism - Identify which clients may require higher doses of CBD due to faster metabolism and which clients may be more prone to drug/drug interactions so you can help clients with pain relief, sleep, anxiety and more


    Subjective Response to THC - Know which genetic variants may make certain people more prone to paranoia or anxiety so you can mitigate negative effects through correct balance of terpenes, cannabinoids, and other factors


    Cannabinoid Receptor Dynamics - Genetic variants that influence receptor density and sensitivity to better understand your client's biology.


    Genetic Influences on Stress Response - Help your clients understand their resiliency vs risk factors in the EC system so you can identify how cannabinoids can help improve stress response


    THC Metabolism - Learn how to screen for genetic factors that impair THC metabolism and make certain people hypersensitive to THC so you can better predict proper dosages


    Cannabis Dependence and Withdrawal - Identify genetic variants associated with addictive tendencies so you can holistically weave this into working with clients that want to reduce or change their usage

Course Curriculum

  • 1

    Welcome to the Course!

    • Welcome To The Course!

    • Navigating the Course

    • Download Course Content Here

  • 2

    Intro to Systems Thinking and Genomics

    • Understanding Systems Thinking

    • Understanding Genomics

  • 3

    Module 1: Introduction To The Endocannabinoid System

    • 1.1 The Endocannabinoid System Overview

    • 1.2 Anandamide

    • 1.3 FAAH

    • 1.4 2-AG

    • 1.5 MAGL_MGLL

    • 1.6 CB1 Receptors

    • 1.7 CB2 Receptors

    • Module 1 Quiz

    • Apeiron Endocannabinoid Report Overview

    • Endocannabinoid Levels Section - Apeiron Report Overview

  • 4

    Module 2: Modulating the Endocannabinoid System

    • 2.1 Cannabinoids

    • 2.2 Terpenes

    • 2.3 Dietary and Lifestyle Factors

    • Module 2 Quiz

  • 5

    Module 3: Stress Response

    • 3.1 Stress Response

    • Module 3 Quiz

    • Stress Response Section - Apeiron Report Overview

  • 6

    Module 4: CB1 Receptor Dynamics

    • 4.1 Receptor Density

    • 4.2 Receptor Sensitivity

    • Module 4 Quiz

    • CB1 Density and Sensitivity Section - Apeiron Report Overview

  • 7

    Module 5: Cognitive Function

    • 5.1 Cognitive Function Overview

    • 5.2 COMT Gene

    • 5.3 Other Cognitive Gene Functions

    • Module 5 Quiz

    • Cognitive Function Section - Apeiron Report Overview

  • 8

    Module 6: THC and CBD Metabolism

    • 6.1 THC Metabolism and CYP2C9

    • 6.2 THC Metabolism and CYP3A4, CYP2C19, and ABCB1

    • 6.3 THC Metabolite Clearance

    • 6.4 CBD Metabolism

    • Module 6 Quiz

    • CBD Metabolism Section - Apeiron Report Overview

    • THC Metabolism Section - Apeiron Report Overview

  • 9

    Module 7: Subjective Response

    • 7.1 Subjective Response

    • Module 7 Quiz

    • Subjective Experience Section - Apeiron Report Overview

  • 10

    Module 8: Cannabis and Psychosis Risk

    • 8.1 Psychosis Risk

    • Module 8 Quiz

    • Psychosis Risk Section - Apeiron Report overview

  • 11

    Module 9: Use, Withdrawal and Craving

    • 9.1 Use, Withdrawal, and Craving

    • Module 9 Quiz

    • Use, Craving and Withdrawal Section - Apeiron Report Overview

  • 12

    Module 10: Case Studies

    • Case Study 1

    • Case Study 2

    • Case Study 3

    • Case Study 4

  • 13

    Q&A Calls

    • Call Recording Links

  • 14

    Apeiron Genomics Information

    • Tour of Apeiron Genomics

    • 23andMe v4 Report Information

  • 15

    Certification Information and Coaching Tips

    • Coaching Tips

    • Certification Information


Include additional content to your course curriculum to provide further value to your students.


    4 Case Study Videos - Get examples of real clients so you can see how the pieces fit together and prepare you to start adding value to your practice right away.


    Complete Guide to CBD - Go deeper on understanding routes of delivery, different types of CBD products, vaporization temperatures of different cannabinoids, and what evidence CBD currently has for it so you can navigate the myriad of options in the marketplace.


    5 Q&A Call recordings with test developer, David Krantz, so you can have 100% clarity on the material and discuss how to organically integrate the testing into your current methodology.


Become an early adopter and expert in cannabinoid nutrigenetics.